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UK’S business hotspots revealed

Research reveals the UK’s top 25 regions for mid-market business growth, highlighting emerging innovation hubs like Manchester, Leeds, and Oxford, and underscoring the sector’s vital role in driving regional economic resilience ahead of the Autumn Budget.

  • Research reveals the UK’s top 25 regions for business growth, with Manchester, Leeds and Oxford leading the charge
  • Index of mid-market companies (MMCs) points to continued London dominance, but finds smaller authorities such as Slough and Telford are punching above their weight as innovation epicentres of the country
  • Swindon emerges as climate tech hub with a cluster of renewable energy and clean technology companies, while university ‘spinouts’ play key role in securing inclusion in the innovative ranking for Cambridge and Oxford
  • The findings suggest the UK’s economic story is “no longer written only in its biggest cities”, says Andy Gray, Managing Director of Commercial Mid-Market at NatWest
  • It comes ahead of the Autumn Budget as economic growth enters the spotlight once again

 

A new index of the UK’s hotspots for business growth has identified Manchester, Leeds and Oxford as being among the preeminent areas for mid-market activity in the UK.

The in-depth report from NatWest, which points to the rising powerhouses of opportunity and innovation across the country, found Manchester to be a dynamic hub for creative and digital industries fuelled by MediaCityUK and a thriving start-up scene.

Oxford, meanwhile, is home to research-driven companies that have evolved from university spinouts into mid-market players, with Leeds carving out a reputation in health technology to complement its established financial services sector thanks to its close links to NHS Digital and leading hospitals.

While London remains the largest centre for profit, headcount, and turnover in the mid-market, other parts of the UK begin to feature more prominently when it comes to innovation.

Slough and Telford and Wrekin were among the smaller authorities appearing in the innovative rankings, while Swindon emerged as one of the climate technology hubs of the country thanks to a cluster of renewable energy and clean technology companies in the area.

 

Top 25 regions for mid-market business growth in the UK:

  1. London
  2. Manchester
  3. Leeds
  4. Oxford
  5. Birmingham
  6. Buckinghamshire
  7. North Yorkshire
  8. Edinburgh
  9. Glasgow
  10. Bristol
  11. Cheshire East
  12. Milton Keynes
  13. Belfast
  14. Sheffield
  15. West Northamptonshire
  16. Aberdeen
  17. Wiltshire
  18. Warrington
  19. Cardiff
  20. Windsor and Maidenhead
  21. Solihull
  22. Reading
  23. Cheshire West and Chester
  24. Wakefield
  25. Nottingham

 

The NatWest research, conducted with data company Beauhurst, took into account innovation, profit change, headcount change and turnover as part of the report, which sought to identify the regional hubs that are reshaping the UK’s economic geography.

It puts the spotlight on mid-market companies (MMCs) which turn over between £25m and £500m annually and account for more than a quarter (26%) of employment and 30% of UK economic Gross Value Added* – a key consideration ahead of the Autumn Budget.  

Among the emerging growth centres of the country, researchers pinpointed South Cambridgeshire as being home to a thriving cluster of university spinouts.

The study notes that these research-intensive companies have scaled into the mid-market, particularly in life sciences, giving the area one of the strongest concentrations of innovative companies in the UK.

Aberdeen and Aberdeenshire also perform strongly in the innovative subset, reflecting the area’s long-standing expertise in oil and gas, now being redirected into renewable energy, carbon capture, and wider climate technologies.

Local businesses have benefitted from specialist engineering skills, proximity to North Sea projects, and strong research links, helping the area reinvent itself as a hub for innovation in the UK’s energy transition.

 

Andy Gray, Managing Director of Commercial Mid-Market at NatWest, said: “The UK’s economic story is no longer written only in its biggest cities. Across the country, mid-sized businesses are scaling up, investing in people and creating high-quality jobs. These boom regions demonstrate that entrepreneurial energy and economic resilience can flourish anywhere.”

 

Henri Murison, Chief Executive at The Northern Powerhouse Partnership, said: “While London remains an important location for mid-market businesses, this new report from NatWest clearly points to the impressive growth and innovation that is taking place in the North across both Manchester and Leeds, and their respective neighbours across Cheshire and in Wakefield, as well as North Yorkshire and Sheffield.”

“As the Autumn Budget approaches, we should be backing concrete steps towards adoption and diffusion of innovation in businesses that are seeking to scale up, providing more high skilled jobs in Northern towns and cities, and playing a fundamental part in delivering the UK Government growth mission.”

 

Louise Hellem, Chief Economist at the CBI, said: “This report underlines the vital role the mid-market sector plays in driving regional growth and strengthening our economy. These businesses are not just surviving, they’re expanding, innovating, and investing in their communities. To fully unlock the UK’s potential and develop high growth clusters, we should harness their strengths as part of regional growth plans, ensure they are engaged in shaping local skills plans and have greater access to finance to scale.”

 

With the right support, mid-market companies could contribute an additional £115 billion to turnover and £35 billion of Gross Value Added by 2030 – despite making up just 0.5% of companies in the UK*.

Committed to helping businesses take the action they need to grow, NatWest offers a range of support for MMCs, from funding options to expert knowledge and advice. For more information on the services and support available, visit the NatWest website at www.natwest.com

UK’s Business Growth & Innovation Hotspots

Download our latest report.

Notes to editors

 

Methodology

Beauhurst identified 29,171 active mid-market companies in the UK with annual turnover between £25m and £500m. From this cohort, we identified a subset of 2,874 innovative companies that meet at least one of our three innovation signals: 1. Has spun out of an academic institution 2. Has received a large innovation grant 3. Has been granted a patent.

 

Geographical methodology

Local authorities are identified using the company’s head office or registered address. Where the local authority aligned closely with a single city or town, this was used to represent the area. However, in some cases, where there is a concentration of small local authorities across a town or city and a number of mid-market companies are spread within them, then these local authorities are grouped into a recognisable local area.

 

About NatWest

NatWest serves customers in England, Wales and Western Europe, supporting them with their personal, private, and business banking needs. NatWest helps customers from opening student accounts, to buying their first home, setting up a business, and saving for retirement. Alongside a wide range of banking services, NatWest offers businesses specialist sector knowledge in areas such as manufacturing and technology, as well as access to specialist entrepreneurial support.

 

About the Mid-Market Growth Council

The Mid-Market Growth Council launched in March 2025 - established to support the segment and break down barriers to growth.

It followed the publication of NatWest’s report, ‘The Critical Middle’, which found that MMCs represent just 0.5% of UK companies, yet still account for 26% of employment and 30% of UK economic Gross Value Added (GVA). 

The report identified several obstacles which mid-market businesses need support to overcome, including a lack of data and transparency, insufficient access to skills and infrastructure, and a lack of a collective identity for the segment. 

The Council brings together HM Treasury, the Department of Business and Trade, major trade groups and the private sector. And aim to:

  • Give voice to the mid-market to facilitate growth and success
  • Collate evidence to better understand the specific issues facing mid-market companies
  • Provide tangible suggestions for policy makers and government to implement the recommendations highlighted in the Critical Middle report
  • Galvanise government, trade bodies and industry activity into one sustainable forum, utilising existing regional infrastructure to ensure the segment is championed. 

Leaders of mid-market companies are integral to the work of the Council and to ensuring its output fills the crucial gaps in support.

 

Henri Murison, Chief Executive, Northern Powerhouse Partnership

Since his appointment in 2017, Henri has established the Northern Powerhouse Partnership as a business led organisation which convenes the North together. From having made the case consistently for Northern Powerhouse Rail, to challenging for a better deal for the most disadvantaged from the education system, his team are focused on how government, business and partners can drive the North’s ambitions.

Before joining the Partnership, he worked in senior research and policy roles in policing and financial services, and as a former senior local government figure in Newcastle upon Tyne remains a commentator on regional and wider industrial policy. Since 2020 he has also served as a member of the Royal Society Science, Industry and Translation Committee, and is also currently a member of the Court of Newcastle University.

 

Louise Hellem, Chief Economist, CBI

Louise is the Chief Economist at the CBI and a member of its Executive Committee. Louise and her team provide business leaders with advice on the UK economic outlook and global risks and leads in setting out the business view on economic policy in discussions with senior politicians and policymakers. Louise also oversees the CBI’s economic consultancy business CBI Economics.

Previously, Louise was the Director of Economic Policy at the CBI. Prior to that, Louise spent 13 years at HM Treasury as a member of the Government Economic Service, where she led on a number of different analytical and policy issues, including assessing the economic and distributional impacts of policy measures at fiscal events.

 

*Source – NatWest’s report, ‘The Critical Middle

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